Endocrine Abstracts

Sperm energy management is poorly studied and understood. The present study provides biochemical and morphological evidence that ejaculated human sperm express the mitochondrial citrate carrier (CIC) which is restricted to the midpiece. CIC inhibition by the specific substrate analogue 1,2,3-benzenetricarboxylate (BTA) reduced cholesterol efflux, proteins tyrosine phosphorylation, P-AKT, P-P60src addressing to its functional role in sperm acquisition of fe...